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The reta + cag combination covers more pathways on paper, but it has no trial data of its own
doi: 10.1080/01635581.2015.1073762 283 RoszkowskiS
Ezetimibe acts on the cells lining the intestines (enterocytes) to reduce their ability to take up cholesterol from the intestines
We speculated that this would be a confounder for understanding the metabolomic changes specific to EHS because it would mask some changes that were influenced by both WD and EHS
Evidence from animal studies shows that MaR1, RvD1, RvD2, and RvE1 inhibit excessive proliferation and migration of vascular smooth muscle cells (VSMCs), downregulate adhesion molecules such as vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), and reduce both reactive oxygen species (ROS) production and proinflammatory mediator release [40, 41]
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